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Induction of Human β-Defensin 2 by the Probiotic Escherichia coli Nissle 1917 Is Mediated through Flagellin

Human β-defensin 2 (hBD-2) is an inducible antimicrobial peptide synthesized by the epithelium to counteract bacterial adherence and invasion. Proinflammatory cytokines, as well as certain bacterial strains, have been identified as potent endogenous inducers. Recently, we have found that hBD-2 induc...

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Autores principales: Schlee, Miriam, Wehkamp, Jan, Altenhoefer, Artur, Oelschlaeger, Tobias A., Stange, Eduard F., Fellermann, Klaus
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865783/
https://ncbi.nlm.nih.gov/pubmed/17283097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01563-06
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