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Surface Expression of Toll-Like Receptor 9 Is Upregulated on Intestinal Epithelial Cells in Response to Pathogenic Bacterial DNA

Colonic epithelial cells are constantly exposed to high levels of bacterial DNA in the intestinal lumen and must recognize and respond appropriately to pathogens, while they maintain a tolerance to nonpathogenic commensal bacterial strains. Bacterial DNA is recognized by Toll-like receptor 9 (TLR9)....

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Main Authors: Ewaschuk, Julia B., Backer, Jody L., Churchill, Thomas A., Obermeier, Florian, Krause, Denis O., Madsen, Karen L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865769/
https://ncbi.nlm.nih.gov/pubmed/17325049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01662-06
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