Mucosal Tissue Invasion by Candida albicans Is Associated with E-Cadherin Degradation, Mediated by Transcription Factor Rim101p and Protease Sap5p

The ability of Candida albicans to invade mucosal tissues is a major virulence determinant of this organism; however, the mechanism of invasion is not understood in detail. Proteolytic breakdown of E-cadherin, the major protein in epithelial cell junctions, has been proposed as a mechanism of invasi...

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Detaylı Bibliyografya
Asıl Yazarlar: Villar, C. C., Kashleva, H., Nobile, C. J., Mitchell, A. P., Dongari-Bagtzoglou, A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Fungal and Parasitic Infections
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865768/
https://ncbi.nlm.nih.gov/pubmed/17339363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00054-07
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