Deficiencies of Myeloid Differentiation Factor 88, Toll-Like Receptor 2 (TLR2), or TLR4 Produce Specific Defects in Macrophage Cytokine Secretion Induced by Helicobacter pylori

Helicobacter pylori is a gram-negative microaerophilic bacterium that colonizes the gastric mucosa, leading to disease conditions ranging from gastritis to cancer. Toll-like receptors (TLRs) play a central role in innate immunity by their recognition of conserved molecular patterns on bacteria, fung...

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Hlavní autoři: Obonyo, Marygorret, Sabet, Mojgan, Cole, Sheri P., Ebmeyer, Joerg, Uematsu, Satoshi, Akira, Shizuo, Guiney, Donald G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865764/
https://ncbi.nlm.nih.gov/pubmed/17353291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01794-06
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