The Putative Glycosyltransferase-Encoding Gene cylJ and the Group B Streptococcus (GBS)-Specific Gene cylK Modulate Hemolysin Production and Virulence of GBS

Group B streptococcus (GBS) expresses a hemolysin/cytolysin that plays an important role in pathogenesis. Using the Himar1 transposon mutagenesis system, a hypohemolytic mutant carrying an interrupted cylJ gene was characterized. cylJ, encoding a putative glycosyltransferase, and cylK, whose product...

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Autores principales: Forquin, Marie-Pierre, Tazi, Asmae, Rosa-Fraile, Manuel, Poyart, Claire, Trieu-Cuot, Patrick, Dramsi, Shaynoor
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865723/
https://ncbi.nlm.nih.gov/pubmed/17283108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01565-06
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