BRAF and KRAS Gene Mutations in Intraductal Papillary Mucinous Neoplasm/Carcinoma (IPMN/IPMC) of the Pancreas

The Raf/MEK/ERK (MAPK) signal transduction is an important mediator of a number of cellular fates including growth, proliferation and survival. The BRAF gene is activated by onogenic RAS, leading to cooperative effects in cells responding to growth factor signals. Our study was performed to elucidat...

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Hauptverfasser: Schönleben, Frank, Qiu, Wanglong, Bruckman, Karl C., Ciau, Nancy T., Li, Xiaojun, Lauerman, Margaret H., Frucht, Harold, Chabot, John A., Allendorf, John D., Remotti, Helen E., Su, Gloria H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865507/
https://ncbi.nlm.nih.gov/pubmed/17097223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2006.09.007
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