Deletion of the cruciform binding domain in CBP/14-3-3 displays reduced origin binding and initiation of DNA replication in budding yeast

BACKGROUND: Initiation of eukaryotic DNA replication involves many protein-protein and protein-DNA interactions. We have previously shown that 14-3-3 proteins bind cruciform DNA and associate with mammalian and yeast replication origins in a cell cycle dependent manner. RESULTS: By expressing the hu...

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Main Authors: Yahyaoui, Wafaa, Callejo, Mario, Price, Gerald B, Zannis-Hadjopoulos, Maria
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865385/
https://ncbi.nlm.nih.gov/pubmed/17430600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-27
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