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Lymphocytes from orally tolerized mice display enhanced susceptibility to death by apoptosis when cultured in the absence of antigen in vitro.

The mechanism responsible for the induction of immunological tolerance by oral administration of soluble antigen remains unclear. Here we show that, when cultured in vitro in the absence of antigen, lymphocytes from mice tolerized with a single feed of 25 mg of ovalbumin display an enhanced mortalit...

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Detalhes bibliográficos
Main Authors: Garside, P., Steel, M., Worthey, E. A., Kewin, P. J., Howie, S. E., Harrison, D. J., Bishop, D., Mowat, A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865368/
https://ncbi.nlm.nih.gov/pubmed/8952532
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