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Platelet-derived growth factor causes pulmonary cell proliferation and collagen deposition in vivo.

Platelet-derived growth factor (PDGF) is postulated to play a role in the pathophysiology of pulmonary fibrosis. Recombinant human PDGF-BB administered as a single intratracheal injection in rats causes an increase in peribronchial and perivascular stromal cells on days 2 and 3 after injection as ev...

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Detalhes bibliográficos
Main Authors: Yi, E. S., Lee, H., Yin, S., Piguet, P., Sarosi, I., Kaufmann, S., Tarpley, J., Wang, N. S., Ulich, T. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865324/
https://ncbi.nlm.nih.gov/pubmed/8701993
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