Incidence of chromosome numerical changes in multiple myeloma: fluorescence in situ hybridization analysis using 15 chromosome-specific probes.

The presence of complex karotypes with frequent numerical and structural abnormalities has been reported in 20 to 50% of multiple myeloma (MM) patients. This variability is mainly due to the difficulty of conventional cytogenetics to obtain tumor metaphases representative of all possible neoplastic...

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Autors principals: Tabernero, D., San Miguel, J. F., Garcia-Sanz, M., Nájera, L., García-Isidoro, M., Peréz-Simon, J. A., Gonzalez, M., Wiegant, J., Raap, A. K., Orfão, A.
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865243/
https://ncbi.nlm.nih.gov/pubmed/8686739
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