Reduced virulence of Serpulina hyodysenteriae hemolysin-negative mutants in pigs and their potential to protect pigs against challenge with a virulent strain.

The role of the Serpulina hyodysenteriae hemolysin encoded by the tlyA gene in the pathogenesis of swine dysentery (SD) was studied. tlyA mutants of two S. hyodysenteriae strains (B204 and C5) were tested for virulence in pigs. None of the animals developed SD. However, after infection with wild-typ...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Hyatt, D R, ter Huurne, A A, van der Zeijst, B A, Joens, L A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8188345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.6.2244-2248.1994
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