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CB2 cannabinoid receptor agonist, JWH-015 triggers apoptosis in immune cells: Potential role for CB2 selective ligands as immunosuppressive agents

Cannabinoids are known to interact with CB1 and CB2 receptors expressed in the nervous and immune system, respectively and mediate a wide range of effects, including anti-inflammatory properties. However, cannabinoids that bind CB1 are also psychoactive thereby limiting their clinical use. In this s...

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Main Authors: Lombard, Catherine, Nagarkatti, Mitzi, Nagarkatti, Prakash
Formato: Artigo
Idioma:Inglês
Publicado: 2006
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864948/
https://ncbi.nlm.nih.gov/pubmed/17185040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2006.11.002
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