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Characterization and Expression of the Short Neuropeptide F Receptor in the African Malaria Mosquito, Anopheles gambiae

A short neuropeptide F (sNPF) precursor and a sNPF receptor (sNPFR) were characterized for the mosquito, Anopheles gambiae. The sNPFR was expressed in CHO-K1 cells, and it exhibited high affinity binding, IC(50) ~3–5 nM, for specific sNPFs. sNPF1 potently inhibited forskolin-stimulated cAMP producti...

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Detalhes bibliográficos
Main Authors: Garczynski, Stephen F., Crim, Joe W., Brown, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864938/
https://ncbi.nlm.nih.gov/pubmed/17140700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2006.09.019
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