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Annexin 2 Regulates Intestinal Epithelial Cell Spreading and Wound Closure through Rho-Related Signaling

Epithelial cell migration is a critical event in gastrointestinal mucosal wound healing and is dependent on actin cytoskeletal reorganization. We observed increased expression of an actin regulatory protein, annexin 2, in migrating intestinal epithelial cells. Small interfering RNA (siRNA)-mediated...

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Главные авторы: Babbin, Brian A., Parkos, Charles A., Mandell, Kenneth J., Winfree, L. Matthew, Laur, Oskar, Ivanov, Andrei I., Nusrat, Asma
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864889/
https://ncbi.nlm.nih.gov/pubmed/17322380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060647
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