Murine FLIP Transgene Expressed on Thyroid Epithelial Cells Promotes Resolution of Granulomatous Experimental Autoimmune Thyroiditis in DBA/1 Mice

Granulomatous experimental autoimmune thyroiditis (G-EAT) is induced by mouse thyroglobulin-sensitized splenocytes activated in vitro with mouse thyroglobulin and interleukin-12. In wild-type (WT) DBA/1 recipients of WT donor splenocytes, thyroid lesions reach maximal severity at day 20, with ongoin...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Fang, Yujiang, Wei, Yongzhong, DeMarco, Vincent, Chen, Kemin, Sharp, Gordon C., Braley-Mullen, Helen
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2007
Ämnen:
Regular Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864882/
https://ncbi.nlm.nih.gov/pubmed/17322373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060816
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