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Thymic Stromal Lymphopoietin Transgenic Mice Develop Cryoglobulinemia and Hepatitis with Similarities to Human Hepatitis C Liver Disease

Essential mixed cryoglobulinemia in humans is strongly associated with chronic hepatitis C virus infection. It remains controversial whether liver injury in hepatitis C is primarily attributable to direct viral cytopathic effect or to an immune-mediated response. We characterized the role of cryoglo...

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Autors principals: Kowalewska, Jolanta, Mühlfeld, Anja S., Hudkins, Kelly L., Yeh, Matthew M., Farr, Andrew G., Ravetch, Jeffrey V., Alpers, Charles E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864872/
https://ncbi.nlm.nih.gov/pubmed/17322382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060474
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