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Glyceryl Trinitrate Inhibits Hypoxia/Reoxygenation-Induced Apoptosis in the Syncytiotrophoblast of the Human Placenta : Therapeutic Implications for Preeclampsia

Damage of the placenta resulting from ischemia-reperfusion is important to the pathophysiology of preeclampsia. Here we investigated whether low concentrations of glyceryl trinitrate (GTN), a nitric oxide mimetic with anti-apoptotic properties, inhibit hypoxia/reoxygenation-induced apoptosis in the...

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Detalhes bibliográficos
Main Authors: Belkacemi, Louiza, Bainbridge, Shannon A., Dickinson, Michelle A., Smith, Graeme N., Graham, Charles H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864864/
https://ncbi.nlm.nih.gov/pubmed/17322376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060665
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