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Differential expression of the cytotoxic and hemolytic activities of the ApxIIA toxin from Actinobacillus pleuropneumoniae.

The ApxIIA protein secreted from Actinobacillus pleuropneumoniae is both hemolytic and cytotoxic. However, when the cloned apxII operon is expressed in Escherichia coli, two forms of the ApxIIA protein can be recovered. Toxin which remains intracellular has hemolytic and cytotoxic activities, while...

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Bibliographic Details
Main Authors: Tu, A H, Hausler, C, Young, R, Struck, D K
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC186478/
https://ncbi.nlm.nih.gov/pubmed/8168980
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