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Antihistoplasma effect of activated mouse splenic macrophages involves production of reactive nitrogen intermediates.

The mechanism by which recombinant murine gamma interferon (rMuIFN-gamma) and bacterial lipopolysaccharide (LPS) activate mouse resident splenic macrophages to inhibit the intracellular growth of the fungus Histoplasma capsulatum was examined. Growth inhibition depended on L-arginine metabolism. The...

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Hlavní autoři: Lane, T E, Wu-Hsieh, B A, Howard, D H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC186447/
https://ncbi.nlm.nih.gov/pubmed/8168960
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