Antihistoplasma effect of activated mouse splenic macrophages involves production of reactive nitrogen intermediates.

The mechanism by which recombinant murine gamma interferon (rMuIFN-gamma) and bacterial lipopolysaccharide (LPS) activate mouse resident splenic macrophages to inhibit the intracellular growth of the fungus Histoplasma capsulatum was examined. Growth inhibition depended on L-arginine metabolism. The...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Lane, T E, Wu-Hsieh, B A, Howard, D H
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8168960/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.5.1940-1945.1994
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