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Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis

Pax6 is a pivotal regulator of eye development throughout Metazoa, but the direct upstream regulators of vertebrate Pax6 expression are unknown. In vertebrates, Pax6 is required for formation of the lens placode, an ectodermal thickening that precedes lens development. Here we show that the Meis1 an...

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Autores principales: Zhang, Xin, Friedman, Adam, Heaney, Shaun, Purcell, Patricia, Maas, Richard L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC186446/
https://ncbi.nlm.nih.gov/pubmed/12183364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1007602
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