Nr-CAM is a target gene of the β-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis

β-catenin and plakoglobin (γ-catenin) are homologous molecules involved in cell adhesion, linking cadherin receptors to the cytoskeleton. β-catenin is also a key component of the Wnt pathway by being a coactivator of LEF/TCF transcription factors. To identify novel target genes induced by β-catenin...

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Veröffentlicht in:	Genes Dev
Hauptverfasser:	Conacci-Sorrell, Maralice E., Ben-Yedidia, Tamar, Shtutman, Michael, Feinstein, Elena, Einat, Paz, Ben-Ze'ev, Avri
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2002
Schlagworte:	Research Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186445/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.227502
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