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Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kilodalton antigen.

Recent advances in the development of animal models for Lyme borreliosis have provided means of identifying potential targets for the design of a subunit vaccine to prevent this disease. The C3H/HeN mouse model was used to study several Borrelia burgdorferi antigens from a single isolate for their a...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Probert, W S, LeFebvre, R B
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1994
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186442/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8168958/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.5.1920-1926.1994
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