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YaeL (EcfE) activates the σ(E) pathway of stress response through a site-2 cleavage of anti-σ(E), RseA

Escherichia coli YaeL (EcfE) is a homolog of human site-2 protease (S2P), a membrane-bound zinc metalloprotease involved in regulated intramembrane proteolysis. We have shown previously that YaeL, having essential metalloprotease active site motifs in the cytoplasmic domain, is indispensable for via...

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Bibliographic Details
Main Authors: Kanehara, Kazue, Ito, Koreaki, Akiyama, Yoshinori
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC186437/
https://ncbi.nlm.nih.gov/pubmed/12183368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1002302
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