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Effect of genetic switching of capsular type on virulence of Streptococcus pneumoniae.

To assess the role of capsular serotypes in the virulence of Streptococcus pneumoniae, we have constructed isogenic derivatives differing only in the type of capsule expressed. Strains of types 2, 5, and 6B were converted to type 3 by transformation and selection for an erythromycin resistance marke...

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Bibliographic Details
Main Authors: Kelly, T, Dillard, J P, Yother, J
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC186414/
https://ncbi.nlm.nih.gov/pubmed/8168944
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