Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck

Mitochondrial genomic mutations are found in a variety of human cancers; however, the frequency of mitochondrial DNA (mtDNA) mutations in coding regions remains poorly defined, and the functional effects of mitochondrial mutations found in primary human cancers are not well described. Using MitoChip...

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Autors principals: Zhou, Shaoyu, Kachhap, Sushant, Sun, Wenyue, Wu, Guojun, Chuang, Alice, Poeta, Luana, Grumbine, Lawson, Mithani, Suhail K., Chatterjee, Aditi, Koch, Wayne, Westra, William H., Maitra, Anirban, Glazer, Chad, Carducci, Michael, Sidransky, David, McFate, Thomas, Verma, Ajay, Califano, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863503/
https://ncbi.nlm.nih.gov/pubmed/17456604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610818104
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