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Targeting the β-catenin/TCF transcriptional complex in the treatment of multiple myeloma
Multiple myeloma (MM) is an invariably fatal form of cancer characterized by clonal proliferation of malignant plasma cells in the bone marrow. The canonical Wnt signaling pathway is activated in MM cells through constitutively active β-catenin, a messenger molecule relevant to growth, survival, and...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1863489/ https://ncbi.nlm.nih.gov/pubmed/17452641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610299104 |
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