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Phosphorylation of the mitotic regulator Pds1/securin by Cdc28 is required for efficient nuclear localization of Esp1/separase

Sister chromatid separation at the metaphase-to-anaphase transition is induced by the proteolytic cleavage of one of the cohesin complex subunits. This process is mediated by a conserved protease called separase. Separase is associated with its inhibitor, securin, until the time of anaphase initiati...

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Bibliografski detalji
Glavni autori: Agarwal, Ritu, Cohen-Fix, Orna
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC186323/
https://ncbi.nlm.nih.gov/pubmed/12050115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.971402
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