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Hox11 paralogous genes are essential for metanephric kidney induction

The mammalian Hox complex is divided into four linkage groups containing 13 sets of paralogous genes. These paralogous genes have retained functional redundancy during evolution. For this reason, loss of only one or two Hox genes within a paralogous group often results in incompletely penetrant phen...

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Detalhes bibliográficos
Main Authors: Wellik, Deneen M., Hawkes, Patrick J., Capecchi, Mario R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC186320/
https://ncbi.nlm.nih.gov/pubmed/12050119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.993302
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