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Binding of Paracoccidioides brasiliensis to laminin through surface glycoprotein gp43 leads to enhancement of fungal pathogenesis.

Extracellular matrix protein laminin binds specifically to yeast forms of Paracoccidioides brasiliensis and enhances adhesion of the fungus to the surface of epithelial Madin-Darby canine kidney cells in vitro. Immunoblotting of fungal extracts showed that the gp43 glycoprotein is responsible for ad...

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Udgivet i:Infect Immun
Principais autores: Vicentini, A P, Gesztesi, J L, Franco, M F, de Souza, W, de Moraes, J Z, Travassos, L R, Lopes, J D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186304/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132354/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.4.1465-1469.1994
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