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Competition between rBPI23, a recombinant fragment of bactericidal/permeability-increasing protein, and lipopolysaccharide (LPS)-binding protein for binding to LPS and gram-negative bacteria.

Lipopolysaccharide (LPS)-binding protein (LBP) and bactericidal/permeability-increasing protein (BPI) are two structurally related lipid A-binding proteins with divergent functional activities. LBP mediates activation of macrophage and other proinflammatory cells. In contrast, BPI has potent bacteri...

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Published in:Infect Immun
Main Authors: Gazzano-Santoro, H, Mészáros, K, Birr, C, Carroll, S F, Theofan, G, Horwitz, A H, Lim, E, Aberle, S, Kasler, H, Parent, J B
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186254/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.4.1185-1191.1994
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