Thiol–disulfide exchange is involved in the catalytic mechanism of peptide methionine sulfoxide reductase

Peptide methionine sulfoxide reductase (MsrA; EC 1.8.4.6) reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulfoxide, Met(O), to methionine. MsrA activity is independent of bound metal and cofactors but does require reducing equiv...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lowther, W. Todd, Brot, Nathan, Weissbach, Herbert, Honek, John F., Matthews, Brian W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10841552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.12.6463
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