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Vaccinia Virus Infection of Mature Dendritic Cells Results in Activation of Virus-Specific Naïve CD8(+) T cells: A Potential Mechanism for Direct Presentation

Understanding how vaccinia virus (VV) generates immunity necessitates an appreciation for how this virus interacts with dendritic cells (DC), which are the most potent activators of naïve CD8(+) T cells. In order to optimally activate naïve CD8(+) T cells, DC must undergo maturation, during which co...

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Autori principali: Yates, Nicole L., Alexander-Miller, Martha A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861836/
https://ncbi.nlm.nih.gov/pubmed/17056088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.09.020
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