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Biophysical Studies of the c-MYC NHE III(1) Promoter: Model Quadruplex Interactions with a Cationic Porphyrin

Regulation of the structural equilibrium of G-quadruplex-forming sequences located in the promoter regions of oncogenes by the binding of small molecules has shown potential as a new avenue for cancer chemotherapy. In this study, microcalorimetry (isothermal titration calorimetry and differential sc...

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Detalhes bibliográficos
Main Authors: Freyer, Matthew W., Buscaglia, Robert, Kaplan, Kimberly, Cashman, Derek, Hurley, Laurence H., Lewis, Edwin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861781/
https://ncbi.nlm.nih.gov/pubmed/17172304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.097246
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