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Biophysical Studies of the c-MYC NHE III(1) Promoter: Model Quadruplex Interactions with a Cationic Porphyrin
Regulation of the structural equilibrium of G-quadruplex-forming sequences located in the promoter regions of oncogenes by the binding of small molecules has shown potential as a new avenue for cancer chemotherapy. In this study, microcalorimetry (isothermal titration calorimetry and differential sc...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Biophysical Society
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1861781/ https://ncbi.nlm.nih.gov/pubmed/17172304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.097246 |
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