Interleukin-6 (IL-6) production in mice infected with Trypanosoma cruzi: effect of its paradoxical increase by anti-IL-6 monoclonal antibody treatment on infection and acute-phase and humoral immune responses.

Trypanosoma cruzi infection of mice triggered endogenous production of interleukin-6 (IL-6) during the ascending phase of parasitemia. Injections of anti-IL-6 monoclonal antibody in infected mice at the time of the serum IL-6 peak paradoxically increased IL-6 levels to 60- to 80-fold those in infect...

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Hauptverfasser: Truyens, C, Angelo-Barrios, A, Torrico, F, Van Damme, J, Heremans, H, Carlier, Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC186159/
https://ncbi.nlm.nih.gov/pubmed/8300226
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