Decreased DNA repair but normal apoptosis in ultraviolet-irradiated skin of p53-transgenic mice.

p53 tumor suppressor plays a vital role in the cellular responses to genotoxic stress. It is believed that p53 regulates the cell cycle by activating the G1 checkpoint after exposure to agents like ionizing radiation, ultraviolet (UV) radiation, or genotoxic chemicals. Recently, it is conjectured th...

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Главные авторы: Li, G., Mitchell, D. L., Ho, V. C., Reed, J. C., Tron, V. A.
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861540/
https://ncbi.nlm.nih.gov/pubmed/8644854
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