Copy-choice recombination by reverse transcriptases: Reshuffling of genetic markers mediated by RNA chaperones
Copy-choice recombination efficiently reshuffles genetic markers in retroviruses. In vivo, the folding of the genomic RNA is controlled by the nucleocapsid protein (NC). We show that binding of NC onto the acceptor RNA molecule is sufficient to enhance recombination, providing evidence for a mechani...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2000
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18612/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10829081/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.120520497 |
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