Construction of a series of congenic mice with recombinant chromosome 1 regions surrounding the genetic loci for resistance to intracellular parasites (Ity, Lsh, and Bcg), DNA repair responses (Rep-1), and the cytoskeletal protein villin (Vil).

The interval of mouse chromosome 1 extending from Idh-1 to Pep-3 harbors the natural resistance gene Ity/Lsh/Bcg; it controls the outcome of infection with Salmonella typhimurium, Leishmania donovani, and several Mycobacterium species. This region also contains a DNA repair gene, Rep-1, which determ...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Autores principales:	Mock, B A, Holiday, D L, Cerretti, D P, Darnell, S C, O'Brien, A D, Potter, M
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1994
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186106/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8262646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.1.325-328.1994
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