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Variations in the ospB gene of Borrelia burgdorferi result in differences in monoclonal antibody reactivity and in production of escape variants.

An escape variant of Borrelia burgdorferi, selected with a monoclonal antibody to OspB, expressed a truncated form of OspB, the result of point mutations in the ospB gene leading to a premature termination codon. A single amino acid position in the C terminus of OspB was critical for monoclonal anti...

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Detaylı Bibliyografya
Yayımlandı:Infect Immun
Asıl Yazarlar: Coleman, J L, Rogers, R C, Rosa, P A, Benach, J L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1994
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7505260/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.1.303-307.1994
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