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Effect of lipopolysaccharide (LPS) chain length on interactions of bactericidal/permeability-increasing protein and its bioactive 23-kilodalton NH2-terminal fragment with isolated LPS and intact Proteus mirabilis and Escherichia coli.

The target-specific cytotoxicity for gram-negative bacteria and the endotoxin-neutralizing activity of the 55-kDa bactericidal/Permeability-increasing protein (BPI) and its bioactive 23-kDa NH2-terminal fragment depend on the strong attraction of BPI for the lipid A region of lipopolysaccharides (LP...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Capodici, C, Chen, S, Sidorczyk, Z, Elsbach, P, Weiss, J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8262637/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.1.259-265.1994
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