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Comparison of conjugates composed of lipopolysaccharide from Shigella flexneri type 2a detoxified by two methods and bound to tetanus toxoid.

Shigella flexneri type 2a lipopolysaccharide (LPS) was detoxified with acetic acid (O-SP) or with hydrazine (DeALPS). DeALPS, but not O-SP, retained part of its lipid A. Both gave an identical line of precipitation with typing antiserum by double immunodiffusion, and both had low levels of LPS activ...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Polotsky, V Y, Robbins, J B, Bryla, D, Schneerson, R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8262629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.1.210-214.1994
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