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Phosphodiesterase type 5 inhibition does not reverse endothelial dysfunction in patients with coronary heart disease

OBJECTIVES: To investigate whether sildenafil citrate, a selective phosphodiesterase type 5 inhibitor, may improve endothelial vasomotor and fibrinolytic function in patients with coronary heart disease. DESIGN: Randomised double blind placebo controlled crossover study. PATIENTS AND METHODS: 16 mal...

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Detalhes bibliográficos
Main Authors: Robinson, S D, Ludlam, C A, Boon, N A, Newby, D E
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860771/
https://ncbi.nlm.nih.gov/pubmed/15863522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2004.059683
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