Evidence that L-(+)-lactate dehydrogenase deficiency is lethal in Streptococcus mutans.

In order to construct an effector strain for the replacement therapy of dental caries, we wished to combine the properties of low-level acid production and high-level colonization potential in a strain of Streptococcus mutans. To this end, we made a deletion in the lactate dehydrogenase (LDH) gene c...

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Publicado en:	Infect Immun
Autores principales:	Hillman, J D, Chen, A, Duncan, M, Lee, S W
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1994
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186067/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8262650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.1.60-64.1994
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