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Aberrant gene methylation implicated in the progression of monoclonal gammopathy of undetermined significance to multiple myeloma

Malignant transformation is a multistep process that may involve dysregulation of oncogenes and tumour suppressor genes, and monoclonal gammopathy of undetermined significance (MGUS) is believed to be a precursor of multiple myeloma. To investigate whether aberrant promoter methylation might be invo...

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Detalhes bibliográficos
Main Authors: Chim, Chor‐Sang, Liang, Raymond, Leung, Man‐Hin, Kwong, Yok‐Lam
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860599/
https://ncbi.nlm.nih.gov/pubmed/17213358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2006.036715
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