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Comparison of concentrations of rifampin and a new rifamycin derivative, DL 473, in canine bone.

Constant-infusion experiments were performed in 14 dogs to determine the penetration into bone of rifampin and a new C-3 substituted rifamycin, DL 473. The drugs were assayed in cortical bone and medulla from tibia-femur and cortical and cancellous bone from rib. After identical dosage, the concentr...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Iversen, P, Nielsen, O S, Jensen, K M, Madsen, P O
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186051/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6838192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.2.338
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