A hypothesis to suggest that light is a risk factor in glaucoma and the mitochondrial optic neuropathies

The authors propose that light entering the eye interacts with retinal ganglion cell (RGC) axon mitochondria to generate reactive oxygen intermediates (ROI) and that when these neurons are in an energetically low state, their capacity to remove these damaging molecules is exceeded and their survival...

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Bibliographic Details
Main Authors: Osborne, N N, Lascaratos, G, Bron, A J, Chidlow, G, Wood, J P M
Format: Artigo
Language:Inglês
Published: BMJ Group 2006
Subjects:
Perspective
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860161/
https://ncbi.nlm.nih.gov/pubmed/16424541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.2005.082230
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