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Genotypic analysis of respiratory mucous sulfation defects in cystic fibrosis.

Intracellular dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) has been proposed to alter endosomal acidification. The most widely studied consequence of this defect has been alterations in the biochemical properties of cystic fibrosis (CF) respiratory mucus glycoprotein...

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Bibliographic Details
Main Authors: Zhang, Y, Doranz, B, Yankaskas, J R, Engelhardt, J F
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC186012/
https://ncbi.nlm.nih.gov/pubmed/8675672
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