Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis

Preclinical osteoarthritis (OA) models are often employed in studies investigating disease-modifying OA drugs (DMOADs). In this study we present a comprehensive, longitudinal evaluation of OA pathogenesis in a rat model of OA, including histologic and biochemical analyses of articular cartilage degr...

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Detalhes bibliográficos
Main Authors: Appleton, C Thomas G, McErlain, David D, Pitelka, Vasek, Schwartz, Neil, Bernier, Suzanne M, Henry, James L, Holdsworth, David W, Beier, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860072/
https://ncbi.nlm.nih.gov/pubmed/17284317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2120
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