Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosis

Recent studies have implicated the dying cell as a potential reservoir of modified autoantigens that might initiate and drive systemic autoimmunity in susceptible hosts. A number of subunits of the exosome, a complex of 3'→5' exoribonucleases that functions in a variety of cellular process...

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Bibliographic Details
Main Authors: Schilders, Geurt, Raijmakers, Reinout, Malmegrim, Kelen CR, Walle, Lieselotte Vande, Saelens, Xavier, Vree Egberts, Wilma, van Venrooij, Walther J, Vandenabeele, Peter, Pruijn, Ger JM
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860071/
https://ncbi.nlm.nih.gov/pubmed/17280603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2119
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