STAT3 activation via interleukin 6 trans‐signalling contributes to ileitis in SAMP1/Yit mice

BACKGROUND AND AIM: SAMP1/Yit mice spontaneously develops intestinal inflammation. Previously, we demonstrated that the signal transducer and activator of transcription (STAT)‐3/suppressor of cytokine signalling (SOCS)‐3 pathway is pivotal in human inflammatory bowel disease. In our studies in SAMP1...

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Main Authors: Mitsuyama, K, Matsumoto, S, Rose‐John, S, Suzuki, A, Hara, T, Tomiyasu, N, Handa, K, Tsuruta, O, Funabashi, H, Scheller, J, Toyonaga, A, Sata, M
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2006
Assuntos:
Inflammatory Bowel Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860050/
https://ncbi.nlm.nih.gov/pubmed/16682432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.079343
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