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Carbamylated erythropoietin ameliorates the metabolic stress induced in vivo by severe chronic hypoxia
Ischemia and chronic hypoxia (CH) trigger a variety of adverse effects arising from metabolic stress that injures cells. In response to reduced O(2), hypoxia-inducible factor 1α (HIF-1α) activates erythropoietin (Epo) as well as many other target genes that counteract the effects of O(2) deficiency....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1859963/ https://ncbi.nlm.nih.gov/pubmed/17090665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608814103 |
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